Escina
Escina polvo, also known as aescin, is a natural compound found in the seeds of the Aesculus hippocastanum tree, commonly known as horse chestnut. It is known for its various medicinal properties and has been used in traditional medicine for centuries. One of the primary uses is to support vascular health. It is thought to poseer antiinflamatorios and vasoprotective properties that can aid in reducing inflamación effect and enhaning blood circulación. It is frequent used for varicose veins, shinchen legs, and leg pain, all signs of chronic venous insufficiency. addition, it is well known for it antioxidant cualidades, which can aid in defender cells against harm brought on by free radicals.
Additionally, it has been studied for its potential anti-diseased cells, anti-edematous, and anti-inflammatory effects. Formally, it is used not only as raw material but also for topical use, often added to creams, gels, or lotions, to reduce facial swelling, dark circles, and skin inflammation. So if you need it, text Xi'an Sonwu; Xi'an Sonwu can provide you with pure escin.
Qué Es El Mecanismo de Acción de Escin
1. Antiinflamatorio mecanismo
It was discovered that it could inhibit the release of high mobility group protein B1 from macrófagos and reduce levels of TNF-, IL-1, and IL-6 in macrófagos, which inhibits the activation of NF-B and increases the survival rate of ratones when endotoxemia caused by lipopolysaccharide is estudiado. In addition, the antioxidant activity of it enhances its it anti-inflamatorry capabilities. It can increase the movements of myeloperoxidase, superoxide dismutase, and glutathione peroxidase and reduce serum NO, TNF- , and IL-1 inflamatorry factors. Level, improve the expression and function of glucocorticoid receptors, significativamente reduce the degree of lung damage in endotoxemia ratones, and extend their survival time. Puede inhibir sustancialmente la exudación de inflamatorios tejidos, reducir su permeabilidad, y significativamente afectar edema y daño a varios tejidos.
2. Gastrointestinal protector mecanismo
It can raise TNF-, P-selectin, and GSH-Px in gastric mucosal tissue while deminsing H plus /K plus ATPase, deminución estómago ácido secreción, and aumento SOD, catalasa, and GSH-Px actividades. Vascular célula adhesión molécula-1 niveles proteger ulcerado mucosa tejido. It puede mejorar la expresión de estrecha unión proteína claudina-5, reducir hígado y intestinal mucosa daño causado por endotoxina, and reducir intestinal epitelial barrera disfunción.
In adición, it puede acelerar gastrointestinal motilidad, promover gastrointestinal transmisión, y reducir postoperatorio adherencias. It may estimulate the synthesis of 5-hydroxytryptamine (5-HT) and interact with 5-HT2 receptors, leading to an increase in the release of NO and endógeno prostaglandins (PGs); it can reduce postoperatorative intestinal adhesion; it inhibits acute inflammation, reduces the increase in vascular permeability, restores intestinal motility, accelerates gastrointestinal transmission, inhibits granuloma formación, inhibiciones adhesión producción y promueve la recuperación de motora función.
3. Nervio célula protección mecanismo
Aescin can shurnge oxygen-free radicals, guard against ischemia/reperfusion damage, and aid in restoring function in damaged neural tissue. Sodium fascinates combined with essential fibroblast growth factors can increase the expression of Bcl-2, inhibit nerve cell apoptosis, reduce damage to neurons, nerve axons, and myelin sheaths, promote functional recovery after spinal cord injury, and improve motor function. Hay a un sinérgico protector efecto contra espinal cordón lesión. It can reduce TNF- , MMP-9, COX-2, and prostaglandin E2, enhance the permeabilidad of the the blood-brain barrera, reduce brain water content, and harm the brain of ratones with acute omethoate poisoning. Edema also has an excellent therapeutic effect.
4. Vascular mecanismo
It puede retrasar glucosa absorción y inhibición gástrico vaciado, la transferencia de glucosa desde el estómago a el intestino delgado, y el transporte dentro el cepillo borde de el intestino delgado. It puede subir sangre insulina y insulina niveles, baja suero leptina niveles, regulate alimento inga y energía metabolismo via central y periférico receptor vías, baja hambre, y boost energía metabolismo. Reduce libre tiroxina (FT4) niveles en alto en grasa dietas, aumenta triyodotironina niveles, reduce ATP síntesis, y aumenta ATP consumo a proveer calorías durante tiroides hormona-dependiente procesos a control peso. In adición, it aumenta HDL colesterol niveles sin afectando suero LDL colesterol y triglicéridos metabolismo.
Qué Es Escin Usado Para
1. Varicose veins
2. Edema
Aescin has diurético propiedades that help reduce swelling caused by fluid retention. It promueve the removal of excess fluid from the body and is often used to treat edema associated with conditions such as venous insufficiency, postoperatorative edema, and injury swelling.
An experimental estudio encontrado eso oral administración de it significativamente reducido agudo extremidad edema. El estudio sujetos eran pacientes pade de extremidades inferiores edema. los resultados mostrados que el edema en el tratamiento grupo fue significativamente reducido. Otro estudio examinado el efecto de it on postoperatorio edema. Investigación muestras oral administración puede minimizar tejido edema alrededor heridas después cirugía y acelerar heridas cicatrizar. Estudios tener encontrado que añadirlo a gel formar puede significativamente reducir músculo edema después deporte lesiones y mejorar recuperación efectos.
3. Antiinflamatorio efecto
Due to its antiinflamatorry properties, it is used as a natural antiinflamatorry agent. Inflamación and swelling brought on by varias diseasees, such as arthritis, sports injuries, and postoperatorative recovery, are decreased by it.
An experimental estudio encontrado que it fue administrado a experimental animales, y los resultados mostrados que it podría significativamente reducir inflamatorios marcadores niveles, respuestas, y tejido daño. Otro estudio mirado en su antiinflamatorio efectos sobre artritis. Aplicando it puede reducir artritis síntomas, alivio articular hinchazón, dolor, y limita movilidad. Escin es también ser estudiado a tratar enfermedades relacionadas inflamación, tal as piel inflamación. It is used in topical creams and gels to improve skin tone and reduce inflammation. It is said to improve skin's microcirculation, enhancing skin look and lowering the risk of skin conditions, include dermatitis.
4. Hemorrhoids
Aescin is commonly used to treat hemorrhoids due to its antiinflamatorry and vein-dilating properties. It helps reduce inflammation, shrink shinchado hemorroides, and alivia síntomas such as pain, itching, and malestar.
Resultados de uno estudio mostrado eso oral administración de it significativamente reducido hemorroides dolor y malestar, reducido hemorroides tamaño, y promovido síntoma alivio comparado con un control grupo. Otro estudio mirado en los efectos de it ser añadido a hemorroides tratamiento en gel forma. Investigación resultados mostrar que esto forma puede reducir dolor y malestar en externo hemorroides, reducir hemorroides tamaño, y ayudar promover curar.
Preguntas más frecuentes
1. Follow dosage instructions: Use it as directed by your doctor or on the drug label. According to research, the recommended oral dose is 50-150 milligrams (mg) per day, divided into 2-3 doses.
2. Uso precaución en embarazada y lactante mujeres: Hay hay actualmente limitado datos en la seguridad de it en embarazada y lactante mujeres, so estos grupos debería consultar a médico antes usar.
3. Avoid allergies: If you are allergic to the horse chestnut in the plant or other similar plants (such as capillary permeability-increasing factor), you may be allergic to it. Before use, ensure you do not have an allergic reaction to such substances.
4. Possible side effects: Some side effects may occur when using it, such as indigestion, nausea, vomiting, dizziness, skin allergies, etc. If severe adverse reactions occur, seek medical attention immediately.
If you want to know the escin manufacturer, you can contact Xi'an Sonwu. Click the email, and then you get high-quality Escin.
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